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Alone or with other chemotherapy medicines.
Rituximab. It is used for non hodgkin lymphoma chronic lymphocytic leukemia rheumatoid arthritis granulomatosis with polyangiitis idiopathic thrombocytopenic purpura pemphigus vulgaris myasthenia gravis and epsteinbarr virus positive mucocutaneous ulcers. Rituximab is a monoclonal antibody that targets the cd20 antigen expressed on the surface of pre b and mature b lymphocytes. Non hodgkins lymphoma or chronic lymphocytic leukemia. It targets a protein called cd20 on the surface of the leukaemia and lymphoma cells.
It is used alone in patients with follicular lymphoma or low grade lymphoma that has relapsed or is refractory doesnt respond to treatment. People with serious infections should not receive rituxan. If you used rituximab intravenous when you were pregnant tell your babys doctor. Chronic lymphocytic leukemia cll.
Rituximab is a monoclonal antibody. See important safety including boxed warnings for more information. Rituximab is used alone or in combination with other medicines to treat the following conditions in adults. Upon binding to cd20 rituximab mediates b cell lysis.
With the chemotherapy medicines fludarabine and cyclophosphamide. Rituximab is used to treat certain types of cancer such as non hodgkins lymphoma chronic lymphocytic leukemiait works by slowing or stopping the growth of cancer cells. A severe autoimmune reaction that causes blisters and breakdown of the skin and mucous membranes. Rituxan rituximab is a prescription medicine used to treat adults with.
Rituximab sticks to all the cd20 proteins it finds. Symptoms of granulomatosis with polyangiitis are fever joint pain fatigue and sinusitis. Rituximab is approved to be used in adults either alone or with other drugs to treat. B cell non hodgkin lymphoma nhl that is cd20 positive.
Possible mechanisms of cell lysis include complement dependent cytotoxicity cdc. Patients with cancer who take rituximab intravenous may be at a greater risk of getting a severe health problem called tumor lysis syndrome tlsthis may lead to death. Some brands of.
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